COLOGUARD TESTIMONIALS

Cologuard® reviews: real stories behind the test

Every Cologuard test tells a story. Hear from the extraordinary people who decided to take control of their gut health and get screened for colon cancer.
Exact Sciences | December 2025
Tim smiling and walking side by side with a woman on a street.

20 million tests completed.1 That’s how many screenings have been done with Cologuard since its launch. Beyond the numbers, you may be wondering what individual experiences are like. We hope these stories, as shared by verified Cologuard test users, will provide answers, add to your peace of mind, and encourage you to get screened.

Breaking the stigma of colon cancer

Despite having no symptoms or family history, a Cologuard test would lead to Tim’s stage 3 colon cancer diagnosis after a colonoscopy. Now, embracing the role of 'papa' to his first grandchild and officially cancer-free, Tim is sharing his story to encourage others to get screened at 45.

Tim sitting in his living room as he is being interviewed.

Getting the word out to get screened

For Meghan, it started with asking her doctor if Cologuard could be an option before doing a colonoscopy. It checked all the right boxes for her, since Cologuard was noninvasive, no prep was needed, and it was a test that could be done at home.
Meghan smiling and sitting in her living room as she is being interviewed.

A call to slow down and prioritize self-care

A gentle reminder from her OB-GYN ended up being the push Yla needed to get screened. The convenience of the Cologuard test made it easy for her to face her fears and get tested for colon cancer, which revealed a stage 3 diagnosis after undergoing a colonoscopy.
Yla being interviewed in a park.

When in doubt, use Cologuard first

As a fitness enthusiast, vegetarian, and avid golfer, Scott was in the best shape of his life at age 53. A long-overdue annual exam, a positive Cologuard test that led to a stage 1 colon cancer diagnosis, followed by surgery to remove a tumor the size of a tennis ball, changed his outlook. Today, Scott is an advocate for timely screening as soon as someone becomes eligible.
Scott smiling as he is being interviewed in his living room.

These patient reviews clearly show that the Cologuard test is favored for its convenience, ease of use, and effectiveness. However, it is equally important to highlight what it can’t do, and who shouldn’t use one:

  • Cologuard can detect but not prevent colon cancer
  • A positive Cologuard test is not a colon cancer diagnosis, and requires a colonoscopy
  • It is not for people with a personal or family history of colon cancer, or who were diagnosed with high-risk conditions such as IBS, Crohn’s disease, or chronic ulcerative colitis

Ultimately, as the reviews encourage, the most important thing is to take charge of your gut health and get screened for colon cancer, especially if you’re 45 or older. Reach out to your doctor, research your options, and make choices that feel good and will work best for you.

Safe.
Noninvasive.
FDA-approved.